Autism and HBOT

Autism spectrum disorder (ASD) involves differences in communication, sensory processing, and behavior. Research suggests that some individuals with autism may also experience underlying biological factors such as neuroinflammation, reduced cerebral blood flow, oxidative stress, or mitochondrial dysfunction. Hyperbaric oxygen therapy (HBOT) increases oxygen delivery under pressure, which may help support healthier brain function in areas related to behavior, sensory regulation, and attention. While HBOT is not a cure for autism, some studies report improvements in specific areas of functioning for certain individuals (Rossignol et al., 2009; Bent et al., 2012).

1. Supporting Cerebral Blood Flow and Oxygenation

Some individuals with autism show areas of reduced blood flow in the brain, particularly in regions involved in sensory processing, language, and behavior. HBOT increases the amount of oxygen dissolved in the bloodstream, which can enhance oxygen delivery to areas with low perfusion. Improved oxygenation may help support healthier neuronal activity and overall brain function (Rossignol et al., 2009).

2. Modulating Neuroinflammation

Studies suggest that neuroinflammation may play a role in symptoms experienced by some individuals with ASD. HBOT has been shown to influence inflammatory pathways and support a more regulated immune response. By helping calm inflammation in the brain, HBOT may contribute to improved cognitive and behavioral functioning for certain individuals (Bent et al., 2012).

3. Supporting Cerebral Blood Flow and Oxygenation

Mitochondrial dysfunction—difficulty producing cellular energy—has been observed in some people with autism. HBOT increases oxygen availability, which supports mitochondrial efficiency and cellular energy production. Healthier energy metabolism may help improve focus, stamina, and cognitive clarity (Rossignol & Frye, 2012).

4. Enhancing Neural Connectivity and Healing

HBOT has been shown to stimulate the growth of new blood vessels and support the repair of injured or under-functioning brain tissues. For individuals with autism who experience areas of reduced connectivity or localized neural stress, enhanced oxygenation may help support long-term brain health and communication between neural networks (Efrati & Ben-Jacob, 2014).